Genes for morphogenetic proteins of chaplin and rodlin families in landomycin producer Streptomyces cyanogenus S136
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Streptomyces cyanogenus S136 attracts attention due to rich secondary metabolism and aberrant morphogenesis. LC-MS analysis of S136 showed the production of novel compounds. Sets of genes for small morphogenetic proteins, chaplins and rodlins, are reduced in S136. We revealed rather diverse pattern of their location and abundance in Streptomyces clade.
[1] Yushchuk O, Ostash I, Vlasiuk I, Gren T, Luzhetskyy A, Kalinowski J, Fedorenko V, Ostash B. “Heterologous AdpA transcription factors enhance landomycin production in Streptomyces cyanogenus S136 under a broad range of growth conditions”. Appl Microbiol Biotechnol. 2018 Oct;102(19):8419-8428. doi: 10.1007/s00253-018-9249-1.
[2] Koshla O, Lopatniuk M, Rokytskyy I, Yushchuk O, Dacyuk Y, Fedorenko V, Luzhetskyy A, Ostash B. “Properties of Streptomyces albus J1074 mutant deficient in tRNA(Leu)(UAA) gene bldA”. Arch Microbiol. 2017 Oct;199(8):1175-1183. doi: 10.1007/s00203-017-1389-7.
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