Green method for the synthesis of crotonolactone and its thiosulfonate derivatives
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γ-Crotonolactone as an important intermediate synthetic product with a broad spectrum of biological effects was synthesized using the concept of green chemistry. An oxidation of furfural was carried out under mild conditions and using non-toxic reagents. The interaction of salts of aromatic thiosulfonic acids with γ-crotonolactone in an aqueous medium was studied, and new γ-[4- ((phenylsulfonyl)thio)]crotonic acids were obtained. The structures of the newly synthesized compounds are confirmed by the data of IR and 1 Н NMR spectroscopy.
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