Green method for the synthesis of crotonolactone and its thiosulfonate derivatives

Green chemistry
Proceedings of the 2nd International Scientific Conference «Chemical Technology and Engineering»: June 24–28, 2019, Lviv: Lviv Polytechnic National University, 2018, pp. 271–273


First and Last Name Academic degree E-mail Affiliation
Nataliya Monka Ph.D. vlubenets [at] Lviv Polytechnic National University
Lviv, Ukraine
Anna Nakonechna No nakonechna.a.1989 [at] Lviv Polytechnic National University
Lviv, Ukraine
Viktor Zvarych No viktor.i.zvarych [at] Lviv Polytechnic National University
Lviv, Ukraine
Volodymyr Novikov Sc.D. volodymyr.p.novikov [at] Lviv Polytechnic National University
Lviv, Ukraine
Vira Lubenets Sc.D. vlubenets [at] Lviv Polytechnic National University
Lviv, Ukraine

I and my co-authors (if any) authorize the use of the Paper in accordance with the Creative Commons CC BY license

First published on this website: 03.05.2019 - 15:29

γ-Crotonolactone as an important intermediate synthetic product with a broad spectrum of biological effects was synthesized using the concept of green chemistry. An oxidation of furfural was carried out under mild conditions and using non-toxic reagents. The interaction of salts of aromatic thiosulfonic acids with γ-crotonolactone in an aqueous medium was studied, and new γ-[4- ((phenylsulfonyl)thio)]crotonic acids were obtained. The structures of the newly synthesized compounds are confirmed by the data of IR and 1 Н NMR spectroscopy.


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