Synthesis and antibacterial activity of novel 3-substituted 1-(2-methyl-5-nitrophenyl)-5-oxopyrrolidine derivatives
I and my co-authors (if any) authorize the use of the Paper in accordance with the Creative Commons CC BY license
The synthesis of novel azole derivatives has been accomplished during chemical transformations of the 1-(2-methyl-5-nitrophenyl)-5-oxopyrrolidine-3-carbohydrazide. The structure of the synthesized compounds was determined by NMR and IR spectroscopies. Most of the synthesized compounds were screened for their antibacterial activity against S. aureus, L. monocytogenes, E. coli, and P. aeruginosa bacteria strains
 Y.Sangnoi et al., “A new antibacterial amino phenyl pyrrolidone derivative from a novel marine gliding bacterium Rapidithrix thailandica”, World J. Microbiol. Biotechnol., vol. 30, iss. 3, pp. 11351139, Mar. 2014.
 S.P. Gasparyan et al., “Synthesis of new derivatives of 5-(3,4-dihydro-2Н-pyrrol-5-yl)-pyrimidine”, Russ. J. Org. Chem., vol. 52, iss. 11, pp. 16461653, Nov. 2016.
 V. Mickevičius et al., “Synthesis and Biological Activity of 3-[Phenyl(1,3-thiazol-2-yl)-amino]propanoic Acids and Their Derivatives”, Molecules, vol. 18, iss. 12, pp. 1500015018, 2013.
 N.Y. Wang, et al., “Discovery of Imidazo[2,1-b]thiazole HCV NS4B Inhibitors Exhibiting Synergistic Effect with Other Direct-Acting Antiviral Agents”, J. Med. Chem., vol. 58, iss. 6, pp. 2764–2778, Feb. 2015.