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Using two separate drugs to lose weight can be very effective you'll find combinations before the FDA now awaiting approval. When dealing with weight-loss and the people that go through it one should err on the side of caution and let the FDA do its job and demand some research be done so your public knows the side effects and risks of the medications before we take them. Keep in mind that drug companies are in business to generate income and that they would say anything to keep people on their medications. Researchers discovered that participants using this drug to get a year, dropped excess weight within 4 weeks and have kept the weight off during the entire 56 weeks of the study. Contrave is a combination in the drugs naltrexone and bupropion, which seems to reflect a whole new trend of weight-loss drugs which might be made up of multiple active ingredient, that might make them more efficient and safer. Combo-pilling could be the newest fad or also the newest in the future under scrutiny and thus it is just more publicly known in recent months, comb-pilling to lose weight has been around since the eighties. The biggest reason that utilizing a combination of pills is now popular will be the fact that at the time of right now there are no long term prescription weightloss pills that have been authorized by the FDA besides orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications although some people might of the combinations have been rejected or have yet to be licensed by the FDA. Seizures certainly are a side effect with Contrave and shouldn't be taken in people with seizure disorders. The drug also can raise hypertension and heartbeat, and must not be used in people with a history of cardiac arrest or stroke in the earlier six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy with all the drug. The FDA also warned that Contrave can raise hypertension and heartrate and must stop used in patients with uncontrolled high blood pressure level, along with by anyone with heart-related and cerebrovascular (circulation dysfunction impacting the brain) disease. Patients having a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes having a boxed warning to alert health care professionals and patients to the increased likelihood of suicidal thoughts and behaviors connected with antidepressant drugs. 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