Efficient Synthesis of Conjugated 1,2,4-Triazole Derivatives under Suzuki Cross-Coupling Reactions in the Presence of Ionic Liquids
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The new derivatives of 4-phenyl-4H-1,2,4-triazole were synthesized under palladium catalyzed Suzuki cross-coupling reaction utilizing the intermediate 3,5-bis(4-bromophenyl)-4-phenyl-4H-1,2,4-triazole and boronic acids. The transformations conducted both in the presence of conventional solvents and in ionic liquids resulted in the formation of the conjugated 1,2,4-triazole arrangements in high yields.
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