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The U.S. Food and Drug Administration has approved Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) as treatment selection for chronic weight-loss in addition to a reduced-calorie diet and exercise.
Using two separate drugs to shed pounds can be very effective you'll find combinations before the FDA now awaiting approval. When dealing with weight reduction and the those who go through it you need to err to the side of caution and permit the FDA do its job and demand some research be done so your public understands the side effects and dangers of the medications before we drive them. Keep in mind that drug companies are in business to earn money and that they would say almost anything to keep people on the medications.
Researchers discovered that participants taking this drug to get a year, lost weight within a month and have kept the body weight off through the 56 weeks from the study. Contrave can be a combination in the drugs naltrexone and bupropion, which usually reflect a brand new trend of weight-loss drugs which might be made up of more than one active ingredient, which can make them more effective and safer.
Combo-pilling will be the newest fad or in addition to this the newest ahead under scrutiny and so it is just more publicly known recently, comb-pilling for losing weight has been around since the eighties. The biggest reason that utilizing a combination of pills is now popular will be the fact that at the time of right now there are no long term prescription weightloss pills that have been approved by the FDA besides orlistat. The truly disturbing part is doctors are prescribing these combinations of medications although some people might of the combinations are already rejected or have yet to be approved by the FDA.
Seizures can be a side effect with Contrave and shouldn't be taken in people who have seizure disorders. The drug could also raise blood pressure level and heartbeat, and must not be used in those with a history of heart attack or stroke in the last six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy with all the drug.
The FDA also warned that Contrave can raise blood pressure level and pulse rate and must stop used in patients with uncontrolled high blood pressure, along with by a person with heart-related and cerebrovascular (circulation dysfunction impacting the brain) disease. Patients with a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes using a boxed warning to alert medical researchers and patients towards the increased probability of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for stop smoking.
"There were no signs of depression or suicidal thoughts in trial participants," said Fujioka.