Synthesis, Properties and Application of Amphiphilic Copolymers Based on Poly(fluoroalkylmethacrylate)s With Terminal Peroxide Group

Organic chemistry Department, Lviv Polytechnic National University, Ukraine, Lviv, S. Bandery street 12
Physical and Colloid Chemistry Department, Ivan Franko National University of Lviv, Ukraine, Lviv, Universytetska street 1
Technology of Biologically Active Substances, Pharmacy and Biotechnology Department, Lviv Polytechnic National University, Ukraine, Lviv, S. Bandery street 12

Abstract

Polymers with terminal peroxide fragment were synrhesized via radical polymerization of fluoroalkyl methacrylates. Amphiphilic block-copolymers with hydrophilic block of different structure were synthesized by usage of obtained polymers with terminal peroxide group as macroinitiators. Kinethic peculiarities of polymerization were studied on both stages. The strucrure of polymers were confirmed by IR- and NMR-spectroscopy.

Keywords

fluoroalkyle methacrylate

peroxide group

radical polymerization

controlled synthesis

References

[1] P. C. Nicolson, J. Vogt, "Soft contact lens polymers: an evolution," Biomaterials., vol. 22, pp.3273-3283, 2001.

[2] I. J. Park, S.-B. Lee, C. K. Choi, "Surface Properties of the Fluorine-Containing Graft Copolymer of Poly((perfluoroalkyl)ethyl methacrylate)-gpoly( methyl methacrylate)," Macromolecules., vol. 31, №21, pp. 7555-7558, 1998.

[3] F. Babudri, G. M. Farinola, F. Naso and R. Ragnia, "Fluorinated organic materials for electronic and optoelectronic applications: the role of the fluorine atom," Chem. Commun., 0, vol. , pp.1003-1022, 2007.

[4] J. С. Ravey, A. Gherbi and M.J. Stebe, "Comparative study of fluorinated and hydrogenated nonionic surfactants. I. Surface activity properties and critical concentrations," Progr Colloid Polym Sci, vol. 76 ,
pp.234-241, 1988.

[5] J. C. Knight, P. G. Edwards, S. J. Paisey, "Fluorinated contrast agents for magnetic resonance imaging; a review of recent developments," RSC Advances, vol. 1 , pp.1415-1325, 2011.

[6] H. Lu, F. Su, S. Q. Mei, Ya. Tian, W. Tian, R. H. Johnsona, D. R. Meldrum, "Using fluorinecontaining amphiphilic random copolymers to manipulate the quantum yields of aggregationinduced emission fluorophores in aqueous solutions and the use of these polymers for fluorescent bioimaging", Journal of materials chemistry, vol. 22, pp. 9890-9900, 2012.

[7] M. Wang, H. Liu, L. Li, Yi. Cheng, " A fluorinated dendrimer achieves excellent gene transfection efficacy at extremely low nitrogen to phosphorous ratios," Nature communications., vol. 5, p. 3053, 2014.