Biocidal preparations based on thiosulphonates and biosurfactants

Green chemistry
3rd International Scientific Conference «Chemical Technology and Engineering»: Proceedings – June 21–24th, 2021, Lviv, Ukraine – Lviv: Lviv Polytechnic National University, 2021, pp. 185–187

Authors

First and Last Name Academic degree E-mail Affiliation
Natalija Monka Ph.D. natalia.y.monka [at] lpnu.ua National University of Lviv Polytechnic
Lviv, Ukraine
Ihor Bobalo No Ihor.Bobalo.BT.2017 [at] lpnu.ua National University of Lviv Polytechnic
Lviv, Ukraine
Tetyana Pokynbroda Ph.D. pokynbroda [at] ukr.net Department of Physical Chemistry of Fossil Fuels of the Institute of Physical-Organic Chemistry and Coal Chemistry named after L. M. Lytvynenko of the National Academy of Sciences of Ukraine
Lviv, Ukraine
Alla Prokopalo No zayarnyuka [at] gmail.com Department of Physical Chemistry of Fossil Fuels of the Institute of Physical-Organic Chemistry and Coal Chemistry named after L. M. Lytvynenko of the National Academy of Sciences of Ukraine
Lviv, Ukraine
Olena Karpenko Sc.D. e.v.karpenko [at] gmail.com Department of Physical Chemistry of Fossil Fuels of the Institute of Physical-Organic Chemistry and Coal Chemistry named after L. M. Lytvynenko of the National Academy of Sciences of Ukraine
Lviv, Ukraine

I and my co-authors (if any) authorize the use of the Paper in accordance with the Creative Commons CC BY license

First published on this website: 07.06.2021 - 14:39
Abstract

The deficit of effective biocides and disinfectants for medicine and veterinary determines the need to develop safe drugs, in particular, green synthesis products. Thiosulfoesters and biosurfactants of microbial origin, rhamnolipids, correspond these criteria. The presence of rhamnolipids in the compositions significantly reduces the effective concentrations of biocides, enhances the antimicrobial effect. 

References
  1. Mampuys, P., McElroy, R., Clark, J., Orru, R., & Maesa, B. (2019). Thiosulfonates as Emerging Reactants: Synthesis and Applications. Adv. Synth. Catal., 362, 3–64. https://doi.org/10.1002/adsc.201900864.
  2. Leontiev, R., Hohaus, N., Jacob, C., Martin, C. H. Gruhlke & Alan J. Slusarenko A. (2018). Comparison of the Antibacterial and Antifungal Activities of Thiosulfinate Analogues of Allicin Scientific RePoRtS. 8:6763. DOI:10.1038/s41598-018-25154-9.
  3. Lubenets,V., Vasylyuk, S., Monka, N., Bolibrukh, K., Komarovska-Porokhnyavets, O., Baranovych, D., Musyanovych, R., Zaczynska, E., Czarny, A., Nawrot, U., Novikov, V. (2017). Synthesis and antimicrobial properties of 4-acylaminobenzenethiosulfoacid S-esters. Saudi Pharmaceutical Journal, 25, 266 274. http://dx.doi.org/10.1016/j.jsps.2016.06.07
  4. Lubenets, V., Stadnytska, N., Baranovych, D., Vasylyuk, S., Karpenko, O.,Havryliak, V., Novikov V. (2019). Thiosulfonates: The Prospective Substances against Fungal Infections. In: Fungal Infection. Eds. Érico Silva de Loreto and JulianaSimoni Moraes Tondolo, IntechOpen, London DOI: 10.5772/intechopen.84436
  5. Dmitryjuk, M., Szczotko, M., Kubiak, K.,Trojanowicz, R., Parashchyn, Z., Khomitska, H., Lubenets, V. (2020). S-methyl-(2-methoxycarbonylamino-benzimidazole-5) thiosulfonate as a potential antiparasitic agent—its action on the development of ascaris suum eggs in vitro. Pharmaceuticals, 13(11), 1–11 doi: 10.3390/ph13110332.
  6. Lubenets, V.I. (2003). Thiosulfonates: synthesis and properties. Ukr. khim. Zhurn, 69(3), 114–121.
  7. Sotirova, A., Avramova, T., Lazarkevich, I., Lubenetz, V., Karpenko, O., Galabova, D. (2014). Antibacterial potential of novel synthetic derivatives of 1,4-naphthoquinone and their complexes with biosurfactants. Research Journal of Pharmaceutical, Biological and Chemical Sciences, 5, 530-541.
  8. Lubenets, V., Karpenko, O., Ponomarenko, M., Zahoriy, G., Krychkovska, A., Novikov, V. (2013). Development of new antimicrobial compositions of thiosulfonate structure. Chemistry and Chemical Technology, 7, 119-124 https://doi.org/10.23939/chcht07.02.119

 

Official paper